Product Uses Include Fluorescent Staining Of Actin Filaments In Fixed Tissue Sections And Tissue Culture Cells Preparations. Note: Unlike Many Actin Antibodies, Acti-Stain™ 488 Phalloidin Binds Only To F-Actin Resulting In Low Background Fluorescence. Furthermore, Binding Of F-Actin By Acti-Stain Is Not Appreciably Different Between Species. Preparation Of Stabilized Fluorescent Actin Filaments In Vitro. Actin Staining Is Very Useful In Determining The Structure And Function Of The Cytoskeleton In Living And Fixed Cells. The Actin Cytoskeleton Is A Very Dynamic And Labile Structure In The Living Cell, But It Can Be Fixed With Paraformaldehyde Prior To Probing Or Staining For Actin Structures.